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Article

A ligand-induced conformational change in the Yersinia protein tyrosine phosphatase.

Protein science : a publication of the Protein Society - 1 Sept 1995

Schubert H L, Fauman E B, Stuckey J A, Dixon J E, Saper M A

Abstract excerpt

Protein tyrosine phosphatases (PTPases) play critical roles in the intracellular signal transduction pathways that regulate cell transformation, growth, and proliferation. The structures of several different PTPases have revealed a conserved active site architecture in which a phosphate-binding l...

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Identifiers

PMID: 8528087
DOI: 10.1002/pro.5560040924
PMCID: PMC2143214

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-8528087-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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