Article
Dynamics of the WPD loop of the Yersinia protein tyrosine phosphatase.
Biophysical journal - 1 Aug 2006
Hu Xin, Stebbins C Erec
Abstract excerpt
The bacterial protein tyrosine phosphatase YopH is an essential virulence determinant in Yersinia spp., causing gastrointestinal diseases and the plague. Like eukaryotic PTPases, YopH catalyzes the hydrolysis of the phosphate moiety of phosphotyrosine within a highly conserved binding pocket, whi...
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