Assembly of the U2 small nuclear ribonucleoprotein from Trypanosoma brucei. A mutational analysis.

Article

Assembly of the U2 small nuclear ribonucleoprotein from Trypanosoma brucei. A mutational analysis.

The Journal of biological chemistry - 25 Jun 1993

Günzl A, Cross M, Palfi Z, Bindereif A

Abstract excerpt

trans-Splicing in trypanosomes requires the functions of U2 and U4/U6 small nuclear (sn) RNPs. We have analyzed protein binding and assembly of the Trypanosoma brucei U2 snRNP, using specific antibodies against U2 snRNP proteins and in vitro reconstitution assays of U2 deletion derivatives and hu...

Topics

Animals
Base Sequence
DNA, Protozoan
Molecular Sequence Data
Mutation
Nucleic Acid Conformation
Protein Conformation
RNA, Protozoan
Ribonucleoprotein, U2 Small Nuclear
Trypanosoma brucei brucei

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.