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Article

Human immunodeficiency virus type 1 Vpu has a CD4- and an envelope glycoprotein-independent function.

Journal of virology - 1 Jul 1993

Geraghty R J, Panganiban A T

Abstract excerpt

Vpu is a 16-kDa membrane-associated phosphoprotein that is expressed from the same, singly spliced message as the human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein precursor, gp160. Previous studies suggest that Vpu functions in the late stages of viral replication, possibly in virus egression from the cell. Recently, it has been demonstrated that Vpu functions to allow gp160 to be more...

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Identifiers

PMID: 8510220
DOI: 10.1128/JVI.67.7.4190-4194.1993
PMCID: PMC237788

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Human immunodeficiency virus type 1 Vpu has a CD4- and an envelope glycoprotein-independent function.PMID 8510220Read ↗

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Cell Surface CD4 Inhibits HIV-1 Particle Release by Interfering with Vpu ActivitySemantic proximity Read ↗

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