Article
Human immunodeficiency virus type 1 Vpu has a CD4- and an envelope glycoprotein-independent function.
Journal of virology - 1 Jul 1993
Geraghty R J, Panganiban A T
Abstract excerpt
Vpu is a 16-kDa membrane-associated phosphoprotein that is expressed from the same, singly spliced message as the human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein precursor, gp160. Previous studies suggest that Vpu functions in the late stages of viral replication, possibly in vi...
Topics
- CD4 Antigens
- Cell Fusion
- Cloning, Molecular
- Gene Products, env
- HIV Core Protein p24
- HIV-1
- HeLa Cells
- Human Immunodeficiency Virus Proteins
- Humans
- In Vitro Techniques
- Mutation
- Transfection
- Viral Envelope Proteins
- Viral Regulatory and Accessory Proteins
- Virus Replication