Article
Passover: a gene required for synaptic connectivity in the giant fiber system of Drosophila.
Cell - 4 Jun 1993
Krishnan S N, Frei E, Swain G P, Wyman R J
Abstract excerpt
Passover (Pas) flies fail to jump in response to a light-off stimulus. The mutation disrupts specific synapses of the giant fibers (GFs), command neurons for this response. Pas was cloned from a P element-induced allele. The cDNA encodes a putative membrane protein of 361 amino acids. Null, hypomorphic, and dominant alleles were sequenced. In the adult central nervous system, and in the pupa during GF synapse...
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