Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pediatric molecular oncology. Past as prologue to the future.

Cancer - 15 May 1993

Knudson A G

Abstract excerpt

The great successes in the treatment of childhood cancers have been followed in recent years with a new understanding of the molecular genetic abnormalities that underlie their origin. For some cancers these genetic changes are in oncogenes; in others, they are in antioncogenes, or tumor suppressor genes. Initiating aberrations in the former are associated characteristically with chromosomal translocations, the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Gene Deletion
Share to Genes, myc

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, p53

Share to Genes, Retinoblastoma

Share to Mutation

Share to Neoplasms

Share to Oncogenes

Source

Identifiers

PMID: 8490875
DOI: 10.1002/1097-0142(19930515)71:10+<3320::aid-cncr2820711730>3.0.co;2-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pediatric molecular oncology. Past as prologue to the future.PMID 8490875Read ↗

Pediatric oncology.Semantic proximity Read ↗

Pediatric Neuro-Oncology: Time to Go Molecular.Semantic proximity Read ↗

Genetics of childhood cancer.Semantic proximity Read ↗

Pediatric solid tumor genomics and developmental pliancy.Semantic proximity Read ↗

Pediatric sarcomas: translating molecular pathogenesis of disease to novel therapeutic possibilitiesSemantic proximity Read ↗

Clinical features of molecular pathology of solid tumours in childhood.Semantic proximity Read ↗

Developmental origins and emerging therapeutic opportunities for childhood cancerSemantic proximity Read ↗

Pediatric brain tumors as a developmental disease.Semantic proximity Read ↗

Epigenetic Changes in Pediatric Solid Tumors: Promising New TargetsSemantic proximity Read ↗

Molecular Profiling in Pediatric Cancer Identifies Potential Targeted Therapies.Semantic proximity Read ↗

Genetics of childhood cancer.Semantic proximity Read ↗

Childhood cancer etiology: recent reports.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.