Article
Genetics of childhood cancer.
Clinical orthopaedics and related research - 1 Aug 2002
Ganjavi Hooman, Malkin David
Abstract excerpt
In recent years, knowledge of the molecular genetics of childhood cancers has been increasing at an exponential rate. The study of the molecular mechanisms of oncogenesis has led to an understanding of the role that tumor suppressors, oncogenes, and deoxyribonucleic acid (DNA) repair genes play in development of the disease. Chromosomal translocations can lead to the disruption of growth regulatory genes or the...
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