Article
Genetics of childhood cancer.
British medical bulletin - 1 Oct 1996
Pritchard-Jones K
Abstract excerpt
In the last 5 years, there has been a tremendous increase in understanding of the molecular genetics of several childhood cancers. The genes for more than 10 cancer predisposition syndromes are now cloned and the molecular basis of their functioning is being analysed. The classical model of inherited cancer predisposition being due to mutation of tumour suppressor genes is being expanded to include genes involved...
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