Hypervariability in a minisatellite 3' of the apolipoprotein B gene in patients with coronary heart disease compared with normal controls.

Article

Hypervariability in a minisatellite 3' of the apolipoprotein B gene in patients with coronary heart disease compared with normal controls.

Journal of lipid research - 1 Apr 1990

Friedl W, Ludwig E H, Paulweber B, Sandhofer F, McCarthy B J

Abstract excerpt

Several recent reports have examined whether there is a correlation between the presence of some minor alleles of the highly polymorphic apolipoprotein B gene and atherosclerosis and premature heart disease. The present study extends this investigation. A high-resolution method was used to study...

Topics

Adult
Alleles
Apolipoproteins B
Coronary Disease
DNA, Satellite
Genes
Genetic Linkage
Genotype
Haplotypes
Humans
Male
Middle Aged
Mutation
Restriction Mapping

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.