Article
Analysis of the apolipoprotein B3' hypervariable region in patients with essential hypertension.
Clinical and experimental pharmacology & physiology. Supplement - 1 Jan 1992
Higashimori K, Higaki J, Miki T, Kamitani A, Mikami H, Kumahara Y, Ogihara T
Abstract excerpt
1. The typing of the apolipoprotein B 3' hypervariable region was investigated in hypertensive and normotensive subjects using rapid typing of a variable number of tandemly repeated short DNA sequences (VNTR) by the polymerase chain reaction. 2. In the DNA samples of 89 normotensive and 99 hypertensive patients, 13 different-sized alleles were detected. The most frequent allele has 35 repeat units in both groups...
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