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Article

Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: an updated review.

Gastroenterology - 1 May 1993

Lynch H T, Smyrk T C, Watson P, Lanspa S J, Lynch J F, Lynch P M, Cavalieri R J, Boland C R

Abstract excerpt

Hereditary nonpolyposis colorectal cancer (HNPCC) dates to Warthin's description of family G, which he began studying in 1895. Warthin's observations were not fully appreciated until 1966 when two families with an autosomal dominant inheritance pattern of nonpolyposis colorectal cancer (CRC) and...

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Identifiers

PMID: 8482467
DOI: 10.1016/0016-5085(93)90368-m

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-8482467-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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