Article
Familial colon cancer syndromes: an update of a rapidly evolving field.
Current gastroenterology reports - 1 Oct 2012
Patel Swati G, Ahnen Dennis J
Abstract excerpt
Colorectal cancer (CRC) is a major cause of morbidity and mortality in the world. Up to 30 % of CRCs have evidence of a familial component, and about 5 % are thought to be due to well-characterized inherited mutations. This review will focus on recent developments in the understanding of the individual hereditary CRC syndromes, including Lynch syndrome, familial CRC type X, familial adenomatous polyposis,...
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