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Article

Use of Family History and Genetic Testing to Determine Risk of Colorectal Cancer.

Gastroenterology - 1 Jan 2020

Kastrinos Fay, Samadder N Jewel, Burt Randall W

Abstract excerpt

Approximately 35% of patients with colorectal cancer (CRC) have a family history of the disease attributed to genetic factors, common exposures, or both. Some families with a history of CRC carry genetic variants that cause CRC with high or moderate penetrance, but these account for only 5% to 10% of CRC cases. Most families with a history of CRC and/or adenomas do not carry genetic variants associated with...

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Identifiers

PMID: 31759928
DOI: 10.1053/j.gastro.2019.11.029

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