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Article

A template for the protein kinase family.

Trends in biochemical sciences - 1 Mar 1993

Taylor S S, Knighton D R, Zheng J, Sowadski J M, Gibbs C S, Zoller M J

Abstract excerpt

The crystal structure of the catalytic subunit of cAMP-dependent protein kinase, complexed with ATP and a 20-residue inhibitor peptide, is reviewed and correlated with chemical and genetic data. The striking convergence of the structure with the biochemistry and genetics provides for the first time a molecular basis for understanding how this enzyme functions, as well as an explanation for the highly conserved...

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Identifiers

PMID: 8480367
DOI: 10.1016/0968-0004(93)80001-r

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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