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Article

Regulation of expression of the chondrocytic phenotype in a skeletal cell line (CFK2) in vitro.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Apr 1993

Bernier S M, Goltzman D

Abstract excerpt

We have examined in vitro the spontaneous and regulated expression of phenotypic characteristics associated with differentiated chondrocytes in an established skeletal cell line (CFK2) derived from fetal rat calvariae. Extended culture of CFK2 cells resulted in the appearance of glycosaminoglycans and type II collagen in the cell layer in association with the formation of focal nodes of cells. In addition,...

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Identifiers

PMID: 8475797
DOI: 10.1002/jbmr.5650080412

Genes

PTH
EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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