Regulation of expression of the chondrocytic phenotype in a skeletal cell line (CFK2) in vitro.

doi:10.1002/jbmr.5650080412

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Article

Regulation of expression of the chondrocytic phenotype in a skeletal cell line (CFK2) in vitro.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Apr 1993

Bernier S M, Goltzman D

Abstract excerpt

We have examined in vitro the spontaneous and regulated expression of phenotypic characteristics associated with differentiated chondrocytes in an established skeletal cell line (CFK2) derived from fetal rat calvariae. Extended culture of CFK2 cells resulted in the appearance of glycosaminoglycan...

Topics

Adenylyl Cyclases
Animals
Cartilage
Cell Differentiation
Cell Division
Cell Line
Extracellular Matrix Proteins
Gene Expression Regulation
Parathyroid Hormone
Phenotype
Protein Biosynthesis
Proteoglycans
RNA, Messenger
Rats

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Open in PubMed

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PMID: 8475797
DOI: 10.1002/jbmr.5650080412

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8475797-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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