Article
Calcium homeostasis in Pseudomonas aeruginosa requires multiple transporters and modulates swarming motility.
Cell calcium - 1 Nov 2013
Guragain Manita, Lenaburg Dirk L, Moore Frank S, Reutlinger Ian, Patrauchan Marianna A
Abstract excerpt
Pseudomonas aeruginosa is an opportunistic human pathogen causing severe acute and chronic infections. Earlier we have shown that calcium (Ca(2+)) induces P. aeruginosa biofilm formation and production of virulence factors. To enable further studies of the regulatory role of Ca(2+), we characterized Ca(2+) homeostasis in P. aeruginosa PAO1 cells. By using Ca(2+)-binding photoprotein aequorin, we determined that...
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