Article
The presence of the testicular determining sequence, SRY, in 46,XY females with gonadal dysgenesis (Swyer syndrome).
American journal of obstetrics and gynecology - 1 Dec 1991
Behzadian M A, Tho S P, McDonough P G
Abstract excerpt
Subjects with 46,XY gonadal dysgenesis (Swyer syndrome) have a distinctive phenotype. They are normal or tall in stature, lack somatic anomalies, and possess bilateral rudimentary gonads. Critical Yp deletions have been described in some cases, but in the majority no defects at the molecular leve...
Topics
- Base Sequence
- DNA
- DNA-Binding Proteins
- Female
- Genes
- Genotype
- Gonadal Dysgenesis, 46,XY
- Humans
- Kruppel-Like Transcription Factors
- Molecular Sequence Data
- Polymerase Chain Reaction
- Transcription Factors