Article
Macrophage phenotype regulation by colony-stimulating factors at bone marrow level.
Journal of leukocyte biology - 1 Mar 1993
Wijffels J F, de Rover Z, Kraal G, Beelen R H
Abstract excerpt
Macrophages (m phi s) can be divided into several subpopulations, which differ in phenotype, function, and localization patterns. However, little is known about the mechanisms that regulate this heterogeneity. We investigated whether m phi heterogeneity is regulated by colony-stimulating factors (CSFs) at the bone marrow level. By clonal expansion of bone marrow-derived precursor cells in the presence of CSF-1,...
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