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Article

Frequency and spectrum of glucokinase mutations in an adult Maltese population.

Acta diabetologica - 1 Mar 2022

Pace Nikolai Paul, Grech Celine Ann, Vella Barbara, Caruana Ruth, Vassallo Josanne

Abstract excerpt

AIM: To investigate the frequency and spectrum of glucokinase (GCK) mutations in a cohort of adults from an island population having a high prevalence of diabetes mellitus (DM). METHODS: A single-centre cohort study was conducted, including 145 non-obese adults of Maltese-Caucasian ethnicity with impaired fasting glycaemia (IFG) or non-autoimmune diabetes diagnosed before the age of 40 years. Bidirectional...

Topics

Adult
Cohort Studies
Diabetes Mellitus, Type 2
Germinal Center Kinases
Glucokinase
Humans
Mutation
Phenotype

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 34677673
DOI: 10.1007/s00592-021-01814-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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