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Evidence of distinct gene functional patterns in GC-poor and GC-rich isochores in Bos taurus.

Animal genetics - 1 Jun 2020

Arhondakis S, Milanesi M, Castrignanò T, Gioiosa S, Valentini A, Chillemi G

Abstract excerpt

Vertebrate genomes are mosaics of megabase-size DNA segments with a fairly homogeneous base composition, called isochores. They are divided into five families characterized by different guanine-cytosine (GC) levels and linked to several functional and structural properties. The increased availability of fully sequenced genomes allows the investigation of isochores in several species, assessing their level of...

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PMID: 32069522
DOI: 10.1111/age.12917

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