Article
Genetic mapping of the X-linked dominant mutations striated (Str) and bare patches (Bpa) to a 600-kb region of the mouse X chromosome: implications for mapping human disorders in Xq28.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 1993
Angel T A, Faust C J, Gonzales J C, Kenwrick S, Lewis R A, Herman G E
Abstract excerpt
Striated (Str) and bare patches (Bpa) are X-irradiation-induced, X-linked dominant mouse mutations that are lethal prenatally in hemizygous males. To map the Str mutation, we generated a backcross involving Mus castaneus. Pedigree analysis of 193 affected female and normal male progeny from the c...
Topics
- Animals
- Base Sequence
- Chromosome Mapping
- Crosses, Genetic
- Female
- Genes, Dominant
- Genetic Linkage
- Humans
- Male
- Mice
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Molecular Sequence Data
- Muridae
- Mutation
- X Chromosome