Article
Patchy fur (Paf), a semidominant X-linked gene associated with a high level of X-Y nondisjunction in male mice.
The Journal of heredity - 1 Jan 2000
Lane P W, Davisson M T
Abstract excerpt
Several X-linked mutations that have associated sex chromosomal nondisjunction have been identified in the mouse. We describe a new semidominant X-linked mutation called patchy fur (Paf) that produces an abnormal coat. It maps to the distal end of the murine X chromosome very near the XY pseudoautosomal region. The degree of severity in affected mice is hemizygous males greater than homozygous females greater...
Topics
- Animals
- Chromosome Aberrations
- Crosses, Genetic
- Female
- Genetic Linkage
- Hair Color
- Karyotyping
- Male
- Meiosis
- Mice
- Mutation
- Nondisjunction, Genetic