Association of Hb S/Hb lepore and delta beta-thalassemia/Hb lepore in Sicilian patients: review of the presence of Hb lepore in Sicily.

doi:10.1111/j.1600-0609.1995.tb01822.x

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Article

Association of Hb S/Hb lepore and delta beta-thalassemia/Hb lepore in Sicilian patients: review of the presence of Hb lepore in Sicily.

European journal of haematology - 1 Aug 1995

Mirabile E, Testa R, Consalvo C, Dickerhoff R, Schilirò G

Abstract excerpt

The hemoglobin (Hb) lepore-Boston is a beta-globin structural variant, produced in a reduced amount and formed from the fusion of N-terminus delta-(residues 1-87) and C-terminus beta-chains (residues 116-146). This type of fusion protein is quite common in Southern Italy (Campania, Calabria, and...

Topics

Adolescent
Adult
Child
Child, Preschool
Chromatography, High Pressure Liquid
DNA
Female
Fetal Hemoglobin
Globins
Hemoglobin, Sickle
Hemoglobins
Hemoglobins, Abnormal
Heterozygote
Humans
Male
Mutation
Sicily
beta-Thalassemia

Source

Open in PubMed

Identifiers

PMID: 7543057
DOI: 10.1111/j.1600-0609.1995.tb01822.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7543057-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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