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Article

Rapid analysis of ‐α<sup>3.7</sup> thalassaemia and ααα<sup>anti 3.7</sup> triplication by enzymatic amplification analysis

1 Jan 1993

Abstract excerpt

In this report we describe a PCR-based method for the diagnosis of the most common form of alpha thalassaemia, the -alpha 3.7 deletion which occurs throughout all tropical and subtropical regions of the world. The same procedure also identifies the reciprocal recombinant chromosome (alpha alpha alpha anti 3.7). Restriction mapping of the PCR products has enabled us to distinguish between the type I (-alpha 3.7...

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Identifiers

PMID: 8435317
DOI: 10.1111/j.1365-2141.1993.tb04639.x

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