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Article

A PCR‐based strategy to detect the common severe determinants of α thalassaemia

1 May 1992

Abstract excerpt

A rapid and inexpensive polymerase chain reaction (PCR) based strategy is described which detects the three common, severe alpha thalassaemia determinants observed in southeast Asia (--SEA) and the Mediterranean (--MED and -(alpha)20.5). Oligonucleotide primers have been chosen which allow specific identification of both normal (alpha alpha) and abnormal (--) chromosomes using identical conditions in either the...

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PMID: 1520607
DOI: 10.1111/j.1365-2141.1992.tb08180.x

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