Article
A wingless-dependent polar coordinate system in Drosophila imaginal discs.
Science (New York, N.Y.) - 22 Jan 1993
Couso J P, Bate M, Martínez-Arias A
Abstract excerpt
The patterning of the imaginal discs in Drosophila melanogaster is a progressive process that, like the patterning of the larval epidermis during embryogenesis, requires the activity of segment polarity genes. One segment polarity gene, wingless, encodes a homolog of the mouse proto-oncogene Wnt-1 and plays a prominent role in the patterning of the larval epidermis and the imaginal discs. However, whereas the...
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