Article
Gene structure and expression analysis of the epidermal growth factor receptor, transforming growth factor-alpha, myc, jun, and metallothionein in human ovarian carcinomas. Classification of malignant phenotypes.
Cancer - 15 Jan 1993
Bauknecht T, Angel P, Kohler M, Kommoss F, Birmelin G, Pfleiderer A, Wagner E
Abstract excerpt
This study reports the structure and expression rates of genes of the transforming growth factor-alpha (TGF-alpha) signal transduction pathway (TGF-alpha, epidermal growth factor receptor [EGF-R], jun, myc, and metallothionein [MT]) in 47 specimens of ovarian cancer and 21 nonmalignant tissues. T...
Topics
- Adult
- Aged
- Blotting, Northern
- Carcinoma
- ErbB Receptors
- Female
- Gene Expression
- Genes, jun
- Genes, myc
- Humans
- Metallothionein
- Middle Aged
- Ovarian Neoplasms
- Phenotype
- RNA, Messenger