Article
Molecular characterization of tumour heterogeneity and malignant mesothelioma cell differentiation by gene profiling.
The Journal of pathology - 1 Sept 2005
Sun Xiaojuan, Wei Lei, Lidén Johan, Hui Gao, Dahlman-Wright Karin, Hjerpe Anders, Dobra Katalin
Abstract excerpt
Malignant mesothelioma is an aggressive tumour, characterized by a variable differentiation pattern and poor prognosis. At present, the clinical outcome in patients with malignant mesothelioma is mainly predicted by the morphological phenotype of the tumour. However, this conventional clinicopathological parameter is of limited value, partly because of the biological heterogeneity of this tumour and poor...
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