Article
Glycosylation of neuraminidase determines the neurovirulence of influenza A/WSN/33 virus
1 Nov 1993
Abstract excerpt
The neuraminidase (NA) gene of influenza A/WSN/33 (WSN) virus has previously been shown to be associated with neurovirulence in mice and growth in Madin-Darby bovine kidney (MDBK) cells. Nucleotide sequence analysis has indicated that the NA of WSN virus lacks a conserved glycosylation site at position 130 (corresponding to position 146 in the N2 subtype). To investigate the role of this carbohydrate in viral...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
