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Article

The splotch-delayed (Spd) mouse mutant carries a point mutation within the paired box of the Pax-3 gene.

Genomics - 1 Aug 1993

Vogan K J, Epstein D J, Trasler D G, Gros P

Abstract excerpt

The splotch (Sp) mouse mutant displays defects in neural crest cell migration and neural tube closure and serves as a model for the study of spina bifida, exencephaly, and Waardenburg syndrome type I in humans. Recently, we have described alterations in the Pax-3 gene for the radiation-induced Spr and Sp2H alleles and for the original, spontaneously arising Sp allele. Another allele that arose spontaneously at...

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Identifiers

PMID: 8406487
DOI: 10.1006/geno.1993.1333

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The splotch-delayed (Spd) mouse mutant carries a point mutation within the paired box of the Pax-3 gene.PMID 8406487Read ↗

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