Androgen receptor gene polymorphisms in amyotrophic lateral sclerosis.

doi:10.1016/0960-8966(93)90059-s

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Article

Androgen receptor gene polymorphisms in amyotrophic lateral sclerosis.

Neuromuscular disorders : NMD - 1 May 1993

Garofalo O, Figlewicz D A, Leigh P N, Powell J F, Meininger V, Dib M, Rouleau G A

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is more common in men than in women (male to female ratio of approximately 2:1), suggesting a role for a sex-linked factor in the disease. The recent identification of a mutation of the androgen receptor gene in Kennedy's disease or X-linked bulbospinal neurono...

Topics

Alleles
Amyotrophic Lateral Sclerosis
Base Sequence
Exons
Female
Humans
Male
Molecular Sequence Data
Mutation
Polymorphism, Genetic
Receptors, Androgen
Repetitive Sequences, Nucleic Acid
Sex Characteristics

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