Article
Androgen receptor polymorphisms (CAG repeat lengths) in androgenetic alopecia, hirsutism, and acne.
Journal of cutaneous medicine and surgery - 1 Jul 1998
Sawaya M E, Shalita A R
Abstract excerpt
BACKGROUND: The androgen receptor (AR) is a structurally conserved member of the nuclear receptor superfamily. The amino-terminal domain is required for transcriptional activation and contains a region of polyglutamine encoded by CAG trinucleotide repeats. In humans, the number of CAG repeats is...
Topics
- Acne Vulgaris
- Adult
- Alleles
- Alopecia
- Confidence Intervals
- DNA
- Electrophoresis, Polyacrylamide Gel
- Female
- Hirsutism
- Humans
- Male
- Middle Aged
- Phenotype
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Receptors, Androgen
- Regression Analysis
- Trinucleotide Repeats