Article
Molecular analysis of the androgen receptor gene in Kennedy's disease. Report of two families and review of the literature.
Hormone research - 1 Jan 1997
Lumbroso S, Lobaccaro J M, Vial C, Sassolas G, Ollagnon B, Belon C, Pouget J, Sultan C
Abstract excerpt
We have performed a molecular analysis of the androgen receptor gene in two families with suspected Kennedy's disease (spinal and bulbar muscular atrophy, SBMA) with the aim of making a firm diagnosis of the disease. The 2 patients studied were sporadic cases. Both presented clinical signs compatible with the diagnosis of SBMA: limb and facial muscular weakness of adult onset progressing toward muscular atrophy....
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