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Article

Alignment and comparison of multiple related DNA sequences can be improved by consideration of known patterns of mutation.

DNA sequence : the journal of DNA sequencing and mapping - 1 Jan 1993

Bains W

Abstract excerpt

The rate at which bases are replaced in mammalian DNA is influenced by the sequence involved. I have modified a multiple sequence alignment and comparison program to take account of the observed patterns of base replacement in mammals, and used the program to analyse 100 human Alu sequences. The results show that using a sequence matching matrix based on the actual rate of base replacement, as opposed to...

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Identifiers

PMID: 8400356
DOI: 10.3109/10425179309020823

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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