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Article

Augmentation of antitumor immunity in regional lymph nodes by local immunotherapy.

Biotherapy (Dordrecht, Netherlands) - 1 Jan 1993

Sakita I, Monden T, Nagaoka H, Katsumoto Y, Wakasugi T, Tomita N, Takeda T, Kobayashi T, Shimano T, Mori T

Abstract excerpt

We have previously reported that the antitumor effect of OK-432, a streptococcal preparation, is markedly augmented when injected intratumorally together with fibrinogen (OK-432/fbg) [1]. In order to elucidate the effects of this immunotherapy on regional lymph nodes (RLN), we carried out both morphological and functional analyses of the RLN from colonic cancer patients treated with OK-432/fbg. Computer-aided...

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Identifiers

PMID: 8398569
DOI: 10.1007/BF01877423

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Augmentation of antitumor immunity in regional lymph nodes by local immunotherapy.PMID 8398569Read ↗

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