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Human FLT3/FLK2 gene: cDNA cloning and expression in hematopoietic cells

15 Aug 1993

Abstract excerpt

The human FLT3 cDNA was cloned from a pre-B cell line and characterized. The deduced amino acid sequence shows that FLT3 codes for a receptor-type tyrosine kinase of 993 residues, presenting a strong similarity with the corresponding mouse FLT3/FLK2 protein as well as with the receptors for colony-stimulating factor 1 (CSF1R/FMS) and steel locus factor (SLFR/KIT). An analysis of the expression of the gene using...

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PMID: 8394751
DOI: 10.1182/blood.v82.4.1110.1110

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