Article
Mapping a putative pyruvoyl decarboxylase active site to human cytomegalovirus open reading frame UL77.
Biochemical and biophysical research communications - 16 Aug 1993
Yoakum G H
Abstract excerpt
Human cytomegalovirus is present as an apparently innocuous infection among a large proportion of the adult population that causes serious disease when congenitally transferred (1). Human cytomegalovirus disease may become life threatening when found as an infection of immunocompromised transplant and AIDS patients (1,2). We now map a putative pyruvoyl decarboxylase enzyme prosthetic group, known to be essential...
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