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Article

The human cytomegalovirus UL76 gene regulates the level of expression of the UL77 gene.

PloS one - 30 Jul 2010

Isomura Hiroki, Stinski Mark F, Murata Takayuki, Nakayama Sanae, Chiba Shigeki, Akatsuka Yoshiki, Kanda Teru, Tsurumi Tatsuya

Abstract excerpt

BACKGROUND: Human cytomegalovirus (HCMV) can be reactivated under immunosuppressive conditions causing several fatal pneumonitis, hepatitis, retinitis, and gastrointestinal diseases. HCMV also causes deafness and mental retardation in neonates when primary infection has occurred during pregnancy. In the genome of HCMV at least 194 known open reading frames (ORFs) have been predicted, and approximately...

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Identifiers

PMID: 20689582
DOI: 10.1371/journal.pone.0011901
PMCID: PMC2912765

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