Characterization of a fission yeast gene, gpa2, that encodes a G alpha subunit involved in the monitoring of nutrition.

doi:10.1101/gad.6.12b.2455

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Article

Characterization of a fission yeast gene, gpa2, that encodes a G alpha subunit involved in the monitoring of nutrition.

Genes & development - 1 Dec 1992

Isshiki T, Mochizuki N, Maeda T, Yamamoto M

Abstract excerpt

The Schizosaccharomyces pombe gpa2 gene was cloned by hybridization with a cDNA for Dictyostelium discoideum G alpha 1. It encodes a homolog of G-protein alpha-subunits with 354 amino acids and a predicted molecular mass of 40,522. Disruption of gpa2 slows cell growth but is not lethal. Cells defective in gpa2 mate and sporulate readily in the presence of plentiful nutrition, bypassing the requirement of nitrogen...

Topics

Amino Acid Sequence
Base Sequence
Cloning, Molecular
DNA
Fungal Proteins
GTP Phosphohydrolases
GTP-Binding Protein alpha Subunits
GTP-Binding Proteins
Genes, Fungal
Glucose
Heterotrimeric GTP-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Nutritional Physiological Phenomena

Phenotype

Restriction Mapping

Schizosaccharomyces

Schizosaccharomyces pombe Proteins

Sequence Homology, Amino Acid

Source

Open in PubMed

Identifiers

PMID: 1340462
DOI: 10.1101/gad.6.12b.2455

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1340462-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Characterization of a fission yeast gene, gpa2, that encodes a G alpha subunit involved in the monitoring of nutrition.PMID 1340462Read ↗

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