Article
Mob2p interacts with the protein kinase Orb6p to promote coordination of cell polarity with cell cycle progression.
Journal of cell science - 1 Jan 2003
Hou Ming-Chin, Wiley David J, Verde Fulvia, McCollum Dannel
Abstract excerpt
The molecular mechanisms that temporally and spatially coordinate cell morphogenesis with the cell cycle remain poorly understood. Here we describe the characterization of fission yeast Mob2p, a novel protein required for regulating cell polarity and cell cycle control. Deletion of mob2 is lethal and causes cells to become spherical, with depolarized actin and microtubule cytoskeletons. A decrease in Mob2p...
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