Article
Acute promyelocytic leukemia with the pseudo-Chediak-Higashi anomaly and molecular documentation of t(15;17) chromosomal translocation.
American journal of clinical pathology - 1 May 1993
Symes P H, Williams M E, Flessa H C, Srivastava A K, Swerdlow S H
Abstract excerpt
Two morphologic variants of acute promyelocytic leukemia (AML M3) are recognized--the hypergranular form, in which Auer rods are usually numerous; and the microgranular form. The case of AML M3 reported here lacked numerous Auer rods but was hypergranular and demonstrated prominent giant Chediak-Higashi-like granules in the leukemic cells. Although routine karyotypic studies were inconclusive, at t(15;17)...
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