Article
Morphologic, cytogenetic, and molecular abnormalities in therapy-related acute promyelocytic leukemia.
American journal of clinical pathology - 1 Jun 2005
Yin C Cameron, Glassman Armand B, Lin Pei, Valbuena Jose R, Jones Dan, Luthra Rajyalakshmi, Medeiros L Jeffrey
Abstract excerpt
We describe 17 cases of therapy-related acute promyelocytic leukemia (tAPL). Treatment for the initial neoplasms (mostly carcinomas and non-Hodgkin lymphomas) included radiation and chemotherapy in 11 patients, radiation in 3, and chemotherapy in 3. The interval between the initial neoplasm and tAPL ranged from 17 to 166 months (median, 40 months). Morphologically, all 13 cases with available bone marrow aspirate...
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