Article
Characterization of the MKS1 gene, a new negative regulator of the Ras-cyclic AMP pathway in Saccharomyces cerevisiae.
Molecular & general genetics : MGG - 1 Apr 1993
Matsuura A, Anraku Y
Abstract excerpt
In order to isolate genes that function downstream of the Ras-cAMP pathway in Saccharomyces cerevisiae, a YEp13-based genomic library was screened for clones that inhibit growth of cells with diminished A-kinase activity. One such gene, MKS1, was found to encode a hydrophilic 52 kDa protein that...
Topics
- Amino Acid Sequence
- Base Sequence
- Cyclic AMP
- DNA, Fungal
- Fungal Proteins
- GTP-Binding Proteins
- Genes, Fungal
- Genes, Regulator
- Genotype
- Molecular Sequence Data
- Oligonucleotides, Antisense
- RNA, Messenger
- Repressor Proteins
- Restriction Mapping
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sequence Homology, Amino Acid
- Suppression, Genetic