Resistance of herpes simplex virus type 2 to neomycin maps to the N-terminal portion of glycoprotein C.

doi:10.1128/JVI.67.5.2434-2441.1993

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Resistance of herpes simplex virus type 2 to neomycin maps to the N-terminal portion of glycoprotein C.

Journal of virology - 1 May 1993

Oyan A M, Dolter K E, Langeland N, Goins W F, Glorioso J C, Haarr L, Crumpacker C S

Abstract excerpt

Entry of herpes simplex virus (HSV) into cells is believed to be mediated by specific binding of envelope proteins to a cellular receptor. Neomycin specifically blocks this initial step in infection by HSV-1 but not HSV-2. Resistance of HSV-2 to this compound maps to a region of the genome encodi...

Topics

Animals
Base Sequence
Chromosome Mapping
Clone Cells
Cricetinae
DNA, Recombinant
DNA, Viral
Drug Resistance, Microbial
Gene Deletion
Molecular Sequence Data
Mutation
Neomycin
Recombinant Fusion Proteins
Recombination, Genetic
Simplexvirus
Viral Envelope Proteins
Viral Proteins
Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 8386261
DOI: 10.1128/JVI.67.5.2434-2441.1993
PMCID: PMC237561

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8386261-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics