Article
Increased synthesis of polycistronic mRNA associated with increased polyadenylation by vesicular stomatitis virus.
Virology - 1 Jul 1992
Hutchinson K L, Herman R C, Hunt D M
Abstract excerpt
Electron microscopy suggested that the mRNA produced in vitro by tsG16(I), a temperature-sensitive mutant of vesicular stomatitis virus, contained an increased proportion of polycistronic mRNAs. Using hybrid selection, we found that the poly(A)+ mRNA synthesized in vitro by tsG16(I) contained approximately two to three times more polycistronic mRNA than did poly(A)+ mRNA synthesized in vitro by the parental...
Topics
- Base Sequence
- Chromosome Mapping
- Genes, Viral
- Microscopy, Electron
- Molecular Sequence Data
- Mutation
- Nucleic Acid Hybridization
- Poly A
- RNA, Messenger
- RNA-Directed DNA Polymerase
- Reading Frames