Article
Mutations in the Drosophila gene encoding ribosomal protein S6 cause tissue overgrowth.
Molecular and cellular biology - 1 Apr 1993
Stewart M J, Denell R
Abstract excerpt
We have characterized two P-element-induced, lethal mutations in Drosophila melanogaster which affect the larval hemocytes, mediators of the insect immune response. Each mutant displays larval melanotic tumors characteristic of mutations affecting the insect cellular immune system, and the moribund animals develop grossly hypertrophied hematopoietic organs because of increased cell proliferation and extra rounds...
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