Effect of rearrangements and duplications of the Cys-His motifs of Rous sarcoma virus nucleocapsid protein.

doi:10.1128/JVI.67.2.623-631.1993

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Article

Effect of rearrangements and duplications of the Cys-His motifs of Rous sarcoma virus nucleocapsid protein.

Journal of virology - 1 Feb 1993

Bowles N E, Damay P, Spahr P F

Abstract excerpt

It has been widely documented that the nucleocapsid protein p12 (NC) of Rous sarcoma virus (RSV) has a role in the encapsidation and maturation of the virus genomic RNA during particle formation, and particularly important appear to be the Cys-His motifs of this protein. Since some retroviruses only have one such motif, we have investigated the significance of the two distinct Cys-His motifs of RSV NC. The...

Topics

Amino Acid Sequence
Avian Sarcoma Viruses
Base Sequence
Cysteine
Gene Products, gag
Gene Rearrangement
Genome, Viral
Histidine
Molecular Sequence Data
Mutagenesis, Site-Directed
Mutation
Protein Precursors
RNA, Viral
Repetitive Sequences, Nucleic Acid
Transfection

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Identifiers

PMID: 8380458
DOI: 10.1128/JVI.67.2.623-631.1993
PMCID: PMC237413

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