Point mutations in the proximal Cys-His box of Rous sarcoma virus nucleocapsid protein.

doi:10.1128/JVI.64.10.4978-4987.1990

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Article

Point mutations in the proximal Cys-His box of Rous sarcoma virus nucleocapsid protein.

Journal of virology - 1 Oct 1990

Dupraz P, Oertle S, Meric C, Damay P, Spahr P F

Abstract excerpt

To extend our previous studies of the function of the Cys-His box of Rous sarcoma virus NC protein, we have constructed a series of point mutations of the conserved or nonconserved amino acids of the proximal Cys-His box and a one-amino-acid deletion. All mutants were characterized for production of viral proteins and particles, for packaging and maturation of viral RNA, for reverse transcriptase activity, and...

Topics

Amino Acid Sequence
Animals
Avian Sarcoma Viruses
Capsid
Cells, Cultured
Chick Embryo
Cysteine
Gene Products, gag
Genes, Viral
Histidine
Molecular Sequence Data
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oligonucleotide Probes

RNA, Viral

Transfection

Viral Core Proteins

Viral Proteins

Virion

Source

Open in PubMed Open full text

Identifiers

PMID: 2168981
DOI: 10.1128/JVI.64.10.4978-4987.1990
PMCID: PMC247989

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2168981-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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