Article
Status of Marek's disease virus in established lymphoma cell lines: herpesvirus integration is common.
Journal of virology - 1 Jan 1993
Delecluse H J, Hammerschmidt W
Abstract excerpt
Six cell lines derived from Marek's disease lymphomas of chickens and turkeys were investigated for the status of Marek's disease virus (MDV) DNA. In the transformed T- and B-cell lines, viral DNA could be detected by conventional Southern blot hybridization, by Gardella gel electrophoresis, and by in situ hybridization of metaphase and interphase chromosomes. Integration of viral DNA into the host cell...
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