Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Temporal kinetics of Marek's disease herpesvirus: integration occurs early after infection in both B and T cells.

Cytogenetic and genome research - 1 Jan 2014

Robinson Charmaine M, Cheng Hans H, Delany Mary E

Abstract excerpt

Marek's disease virus (MDV) is an oncogenic α-herpesvirus that induces Marek's disease characterized by fatal lymphomas in chickens. Here, we explored the timing during pathogenesis when the virus integrates into the host genome, the cell type involved, the role of viral integration on cellular transformation, and tumor clonality. Three immune organs of chicken (thymus, bursa, and spleen) were extracted following...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to B-Lymphocytes
Share to Cell Lineage
Share to Chickens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to In Situ Hybridization, Fluorescence

Share to Spleen

Share to T-Lymphocytes

Share to Thymus Gland

Share to Virus Integration

Source

Identifiers

PMID: 25402709
DOI: 10.1159/000368379

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Temporal kinetics of Marek's disease herpesvirus: integration occurs early after infection in both B and T cells.PMID 25402709Read ↗

Virus and host genomic, molecular, and cellular interactions during Marek's disease pathogenesis and oncogenesisSemantic proximity Read ↗

Marek's disease herpesvirus vaccines integrate into chicken host chromosomes yet lack a virus-host phenotype associated with oncogenic transformation.Semantic proximity Read ↗

Status of Marek's disease virus in established lymphoma cell lines: herpesvirus integration is common.Semantic proximity Read ↗

Latest Insights into Marek’s Disease Virus Pathogenesis and TumorigenesisSemantic proximity Read ↗

Immune escape of avian oncogenic Marek’s disease herpesvirus and antagonistic host immune responsesSemantic proximity Read ↗

Marek’s disease virus: lytic replication, oncogenesis and controlSemantic proximity Read ↗

Unraveling the role of γδ T cells in the pathogenesis of an oncogenic avian herpesvirusSemantic proximity Read ↗

Marek’s disease in chickens: a review with focus on immunologySemantic proximity Read ↗

Marek's disease: an update on oncogenic mechanisms and control.Semantic proximity Read ↗

The long view: 40 years of Marek's disease research and<i>Avian Pathology</i>Semantic proximity Read ↗

Clonal Structure of Rapid-Onset MDV-Driven CD4+ Lymphomas and Responding CD8+ T CellsSemantic proximity Read ↗

Ancient chicken remains reveal the origins of virulence in Marek’s disease virusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.